The History & Future of Vaccines: How They’ve Changed the World

Vaccines are a type of medicine that helps to protect against diseases by stimulating the body’s immune system to recognize and fight specific pathogens, such as viruses or bacteria. Vaccines work by introducing a small, harmless piece of a pathogen into the body, which triggers an immune response that helps to build immunity to that pathogen.

There are many different types of vaccines, including inactivated vaccines, live attenuated vaccines, subunit vaccines, and mRNA vaccines. Each type of vaccine uses different methods to introduce the pathogen into the body, and each has its own advantages and disadvantages.

Vaccines have been instrumental in controlling and even eradicating many infectious diseases around the world. For example, smallpox was eradicated in the 1970s thanks to a vaccine that was developed in the 18th century. In recent years, vaccines have also been used to combat outbreaks of diseases such as measles, mumps, and COVID-19.

While vaccines are generally safe and effective, they can cause side effects in some people. Common side effects include soreness at the injection site, fever, and fatigue. Severe side effects are rare, but can include allergic reactions and neurological problems.

Overall, vaccines are an important tool in preventing the spread of infectious diseases and protecting public health. They are widely recommended for children and adults, and are an important part of a comprehensive approach to disease prevention and control. 

Market Analysis: The global vaccines market is expected to reach US$ 64,538.4 Mn in 2027 from US$ 36,998.8 Mn in 2018. The market is estimated to grow with a CAGR of 6.5% from 2019-2027.

Rising prevalence of infectious diseases is expected to boost the market growth over the years

In the current era, there are increasing concerns of spread of infectious diseases with the changing environment. These emerging infectious diseases are a burden on public health but have also an impact on global economies. The new diseases such as HIV, hepatitis, dengue have attracted a huge concern for the government of the respective countries. There is also resurgence of diseases which seemed to be under control such as malaria, cholera and many more. According to the Centers for Disease control and Prevention in 2015, 16.8 million people in the US visited hospitals due to infectious and parasitic diseases. In Africa, chronic viral hepatitis affects around 70 million Africans (60 million with Hepatitis B and 10 million with Hepatitis C).

The disease impacts the most important part of the African population i.e. youths and earning African population which are causing tremendous rise in financial debts incurred for the treatment of advanced liver diseases and emotional distress. In developed countries, the cases of infectious diseases has decreased in the past decade, but there has been a rise of re-emerging diseases worldwide, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), measles, avian and pandemic influenza, chikungunya virus, Ebola virus disease (EVD) and Zika virus disease, which has attracted a renewed focus on infectious diseases around the developed countries. Thus the growing global prevalence of infectious diseases are expected to encourage the leading market players for the development of new and effective drugs and vaccines.

The History of Vaccines:

The history of vaccines dates back thousands of years, with the earliest recorded use of vaccination dating back to ancient China in the 10th century. In China, physicians used the blood of healthy chickens to treat smallpox, and the practice of using animal blood to treat diseases continued for centuries.

In the 18th century, Edward Jenner, an English physician, introduced the concept of vaccination by using cowpox to protect against smallpox. This discovery, known as variolation, was widely adopted and helped to greatly reduce the incidence of smallpox.

In the 19th century, Louis Pasteur and other scientists made significant advances in the understanding of germs and how they spread disease. This led to the development of new vaccines and improved methods of vaccination.

In the 20th century, vaccines became widely available and were instrumental in controlling and even eradicating many infectious diseases. For example, smallpox was eradicated in the 1970s thanks to a vaccine that was developed in the 18th century. In recent years, vaccines have also been used to combat outbreaks of diseases such as measles, mumps, and COVID-19.

Today, vaccines continue to be an important tool in preventing the spread of infectious diseases and protecting public health. They are widely recommended for children and adults and are an important part of a comprehensive approach to disease prevention and control. 

The Future of Vaccines Industry:  

The future of vaccines looks bright, with ongoing research and development aimed at improving existing vaccines and creating new ones to protect against a wide range of diseases. Some of the key areas of focus in the future of vaccines include:

  1. Personalized vaccines: Personalized vaccines are tailored to an individual’s specific genetic makeup, which may help to improve their effectiveness and reduce the risk of side effects.
  2. mRNA vaccines: mRNA vaccines use a small piece of RNA that instructs the body to produce a specific protein, which triggers an immune response. These vaccines have shown promise in the development of vaccines for a variety of diseases, including COVID-19.
  3. Vaccines for emerging diseases: With the increasing threat of new and emerging diseases, there is a need for vaccines that can be developed quickly and effectively to protect against these threats.
  4. Vaccines for older adults: As people live longer, there is a greater need for vaccines that are effective in older adults, who may have weaker immune systems and be at greater risk of serious complications from infectious diseases.
  5. Vaccines for children in low-resource settings: Many children in low-resource settings do not have access to basic vaccines, and there is a need for vaccines that are affordable and easy to transport and store.

Overall, the future of vaccines looks bright, with ongoing research and development aimed at improving existing vaccines and creating new ones to protect against a wide range of diseases. With continued investment in vaccine research and development, it is possible to imagine a future where many of the world’s deadliest diseases are a thing of the past.